MEDIA

EVENTS

Researchers from Fondazione Gianni Benzi cooperated with the team of Dipartimento di Farmacia - Scienze del Farmaco at Università degli Studi di Bari to the articleTISBE: A Public Web Platform for the Consensus-Based Explainable Prediction of Developmental Toxicityrecently published on the Chemical Research in Toxicology journal.

The work describes TISBE (TIRESIA Improved on Structure-Based Explainability), a new public web platform for Developmental Toxicity predictions.

Developmental toxicity, in the framework of prenatal and neonatal health, is a highly complex endpoint. The lack of high-quality data as well as robust non-testing methods makes its understanding even more difficult. Thus, the application of new explainable alternative methods is of utmost importance.

Resulting from TIRESIA (Toxicology Intelligence and Regulatory Evaluations for Scientific and Industry Applications), TISBE implements four fundamental advancements for in silico analyses: a three times larger dataset, a transparent explainable artificial intelligence framework, a novel consensus classifier based on five independent machine learning models, and a new applicability domain method based on a double top-down approach for better estimating the prediction reliability.

TISBE is freely available at: https://prometheus.farmacia.uniba.it/tisbe

Read the article here.

Subscribe To Our Newsletter

to keep you up to date on our activities and initiatives

La tua iscrizione non può essere convalidata.
La tua iscrizione è avvenuta correttamente.

We use Brevo as our marketing platform. By clicking below to submit this form, you are aware and accept that the information you have provided will be transferred to Brevo for treatment in accordance with their terms of use
Utilizziamo Brevo come nostra piattaforma di marketing. Cliccando qui sotto per inviare questo modulo, sei consapevole e accetti che le informazioni che hai fornito verranno trasferite a Brevo per il trattamento conformemente alle loro condizioni d'uso

You have Successfully Subscribed!

Pin It on Pinterest

Share This